Here is an article by the Dr Rath Foundation relating to how drugs deplete our stores of essential nutrients, thus making us more ill and thus making us more dependent on extra drugs.  This creates polypharmacy.

http://www4.dr-rath-foundation.org/Newsletter/articles/Drug-induced-nutrient-depletion-one-of-the-pharma-cartels-biggest-secrets.html?utm_source=email&utm_medium=artikel-link&utm_campaign=newsletter-20160715

It is possible that fluoride has the same effect and, of course, it's present in may drugs.

Joy