Fluoride Free Australia
Time to stop Forced Water Fluoridation.
NEW FLUORIDE STUDY, HOW EVERY HUMAN CELL CAN BE HARMED?
https://www.miragenews.com/molecular-basis-of-clc-transpor…/
"The binding of protons and their transport through the cell membrane are crucial steps for many cellular processes. CLC chloride/proton transporters are present in almost every living cell and regulate the pH value, chloride concentrations and membrane potentials of intracellular cell compartments. Various human diseases, which are caused by dysfunctional CLC transporters and which range from osteopetrosis and kidney dysfunction to epilepsy and mental retardation, illustrate the high physiological and pharmacological impact of this class of membrane proteins.
CLC transporters transport a large number of anions, but are inhibited by fluoride, the smallest anion in the periodic table. Scientists from the Institute of Neurosciences and Medicine (Computational Biomedicine) and the Institute of Biological Information Processing (Molecular and Cellular Physiology) at Forschungszentrum Jülich have used massively parallel hybrid quantum mechanical/classical mechanical simulations to investigate how these chloride transporters differentiate between the anions and what happens when fluoride binds to the protein. In a process that can be described only at the quantum mechanical level, fluoride simultaneously binds protons and an amino acid side chain, which usually shuttles protons across the membrane. This locks the CLC transporter in a fixed position and inhibits the transport process."
The study. https://pubs.acs.org/doi/10.1021/jacs.9b13588…
Learn more. https://fluoridefreeaustralia.org/
NEW FLUORIDE STUDY, HOW EVERY HUMAN CELL CAN BE HARMED?
https://www.miragenews.com/molecular-basis-of-clc-transpor…/
"The binding of protons and their transport through the cell membrane are crucial steps for many cellular processes. CLC chloride/proton transporters are present in almost every living cell and regulate the pH value, chloride concentrations and membrane potentials of intracellular cell compartments. Various human diseases, which are caused by dysfunctional CLC transporters and which range from osteopetrosis and kidney dysfunction to epilepsy and mental retardation, illustrate the high physiological and pharmacological impact of this class of membrane proteins.
CLC transporters transport a large number of anions, but are inhibited by fluoride, the smallest anion in the periodic table. Scientists from the Institute of Neurosciences and Medicine (Computational Biomedicine) and the Institute of Biological Information Processing (Molecular and Cellular Physiology) at Forschungszentrum Jülich have used massively parallel hybrid quantum mechanical/classical mechanical simulations to investigate how these chloride transporters differentiate between the anions and what happens when fluoride binds to the protein. In a process that can be described only at the quantum mechanical level, fluoride simultaneously binds protons and an amino acid side chain, which usually shuttles protons across the membrane. This locks the CLC transporter in a fixed position and inhibits the transport process."
The study. https://pubs.acs.org/doi/10.1021/jacs.9b13588…
Learn more. https://fluoridefreeaustralia.org/
posted by Bill at
9:34 AM
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