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UK Against Fluoridation

Saturday, March 18, 2017

HARVARD: IMPACT OF FLUORIDE ON NEUROLOGICAL DEVELOPMENT IN CHILDREN

......................However, the developing human brain may be exposed prenatally to fluoride as fluoride readily crosses the placenta (ATSDR, 2003). In laboratory studies, the central nervous system (CNS) may be vulnerable to fluoride. Fluoride accumulates in brain tissues and may affect the hippocampus, the central processor of memory, in learning and memory functions (Mullenix et al., 1995 and Chioca et al., 2008). Potential effects on the neurodevelopment in children have been explored mainly in China where many urban and rural communities are located in endemic fluorosis areas. Thus, a National Research Council report reviewed the effects of fluoride in drinking water on human health, including the cognitive capacities in children (NRC, 2006). Many relevant studies were identified that, collectively, supported the hypothesis that fluoride is a developmental neurotoxicant, but because many of the studies did not provide sufficient information about the neurobehavioral tests used and the testing conditions, the report recommended that additional, more rigorous research be conducted......

Conclusions

This pilot study in a community with stable lifetime fluoride exposures supports the notion that fluoride in drinking water may produce developmental neurotoxicity, and that the dose-dependence underlying this relationship needs to be characterized in detail.

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