Early signs of fluoride poisoning

Early signs of fluoride poisoning Researchers examining 112 cases of fluorosis in Ontario, Ohio, Italy and British Columbia found the following collective symptoms (Fluoride, 1998; 31: 13-20), which tend to appear before the bones are affected:
Musculo skeletalArthritis, especially in the cervical and lumbar spine, muscle pain, pins and needles, inability to control extremities. Gastro intestinal Gastric pain, nausea, vomiting, bloating, diarrhoea, constipation, acute abdominal episodes, inflammation of the mouth. Neurological Migraine like headaches, blurred vision with moving spots, convulsions, muscular fibrillation. Respiratory Nasal and conjunctival problems, emphysema, asthma, nose bleeds. Skin
Dermatitis, inflammation around capillary blood vessels. Other symptoms Cough, excess mucus, breathing difficulties, mouth ulcers, bleeding gums, palpitations, vertigo, difficulty sleeping, excessive thirst, excessive urination, frequent episodes of lower urinary tract disease, oedema in hands and ankles, joint pains, stiffness, rheumatic pains, rash, marked mental deterioration mainly memory loss and ability to concentrate tinnitus, fatigue and extreme exhaustion. Many people became bedridden.

Sounds extreme.